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Structure of 41340-78-7
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N,N-Dimethylpiperazine-1-carboxamide features a sterically hindered piperazine core with dual dimethylamino groups, enhancing solubility and metabolic stability. The carboxamide functionality provides a robust hydrogen-bonding motif for target engagement. This compound serves as a key scaffold in medicinal chemistry, integrating well into bioactive molecules requiring balanced lipophilicity and polarity.
N,N-Dimethylpiperazine-1-carboxamide serves as a versatile amide building block in medicinal chemistry, offering enhanced solubility and metabolic stability compared to simpler alkyl amides. Its piperazine core provides a rigid, polar scaffold ideal for modulating pharmacokinetic properties. The dimethylamino groups enhance basicity and hydrogen-bonding capacity, facilitating interactions with biological targets. This compound functions effectively in coupling reactions and acts as a key intermediate in the synthesis of heterocyclic APIs and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: