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Structure of 4144-64-3
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1H-1,2,3-Benzotriazol-1-ylacetic acid features a benzotriazole moiety linked to a carboxylic acid group, enabling efficient coupling in peptide synthesis. This derivative combines the activating power of benzotriazole with enhanced solubility and stability under standard conditions, facilitating clean reaction profiles and high yields in amide bond formation.
1H-1,2,3-Benzotriazol-1-ylacetic acid serves as a versatile acylating agent in peptide synthesis and small-molecule conjugation, enabling efficient formation of amide bonds under mild conditions. Its benzotriazole leaving group ensures high reactivity with nucleophiles while maintaining bench stability and ease of purification. Functions effectively in standard coupling protocols, offering good functional group tolerance and compatibility with common protecting groups in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: