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CS-W001157 4
Total: USD 88.00

(3aR,5R,6S,6aR)-2,2,5-Trimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol

  • CAS No. 4152-79-8

  • Cat. No. CS-0255193
  • Molecule weight174.19
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3aR,5R,6S,6aR)-2,2,5-Trimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol|CS-0255193

Structure of 4152-79-8

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General Information

  • CAS No. 4152-79-8
  • Cat. No. CS-0255193
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄O₄
  • Molecular Weight 174.19
  • Synonym(s) 2,2,5-Trimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol
  • SMILES O[C@@H]1[C@]2([H])[C@@](O[C@@H]1C)([H])OC(C)(O2)C

Synthesis

  • Route1
    • (3AR,5S,6R,6aR)-5-(iodomethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol|CS-0504880
      50600-39-0
    • ~89%
    • (3aR,5R,6S,6aR)-2,2,5-Trimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol|CS-0255193
      4152-79-8

    References

    • Nguyen, John D.; D'Amato, Erica M.; Narayanam, Jagan M. R.; Stephenson, Corey R. J. Nature Chemistry, 2012 , vol. 4, # 10 p. 854 - 859
  • Route2
    • null|null
      6893-65-8
    • ~10%
    • (3aR,5R,6S,6aR)-2,2,5-Trimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol|CS-0255193
      4152-79-8

    References

    • Kang, Suk-Ku; Cho, Hyun-Sung Tetrahedron Letters, 1991 , vol. 32, # 3 p. 367 - 370
  • Route3
    • null|null
      4118-63-2
    • ~76%
    • (3aR,5R,6S,6aR)-2,2,5-Trimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol|CS-0255193
      4152-79-8

    References

    • Aventis Pharmaceuticals, Inc.; Hoechst Marion Roussel Deutschland GmbH Patent: EP1734037 A2, 2006 ; Location in patent: Page/Page column 49 ;

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   47.92
  • LogP   0.2436
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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