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Structure of 415965-24-1
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4-Bromo-2-fluoro-5-methylbenzoic acid features a trifunctional aromatic core with halogen and alkyl substituents that enable precise functionalization in medicinal chemistry. The electron-deficient ring facilitates coupling reactions, while the carboxylic acid group provides a handle for derivatization. This bench-stable reagent integrates readily into complex molecular architectures under standard conditions.
4-Bromo-2-fluoro-5-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into biologically active scaffolds via standard coupling reactions. Its orthogonal functionalization—combining bromine for cross-coupling, fluorine for metabolic stability, and a methyl group for steric modulation—facilitates efficient derivatization. The carboxylic acid functionality enables amide formation and esterification under mild conditions, offering robust access to diverse analogs with predictable reactivity profiles. Bench-stable and readily purified by recrystallization, it supports scalable synthesis and reproducible workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: