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Structure of 41716-18-1
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1-Methyl-1H-imidazole-4-carboxylic acid features a polar, electron-deficient imidazole core paired with a carboxylic acid handle, enabling direct conjugation in peptide synthesis and bioconjugation workflows. This bench-stable derivative integrates readily into heterocyclic scaffolds requiring hydrogen-bonding capacity and moderate lipophilicity.
1-Methyl-1H-imidazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, offering a readily functionalizable imidazole core with enhanced solubility and stability. The carboxylic acid group enables direct coupling reactions for peptide and ester formation, while the N-methyl substitution improves metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient integration into API and fragment libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: