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CS-W001157 4
Total: USD 88.00

Methyl (E)-3-(3-formyl-4-hydroxyphenyl)acrylate

  • CAS No. 417712-26-6

  • Cat. No. CS-0200423
  • Purity≥97%
  • MDL No.MFCD22575202
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl (E)-3-(3-formyl-4-hydroxyphenyl)acrylate|CS-0200423

Structure of 417712-26-6

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Description

Methyl (E)-3-(3-formyl-4-hydroxyphenyl)acrylate features a conjugated enone system flanked by a phenolic hydroxyl and aldehyde functional group, enabling direct participation in Diels-Alder cycloadditions and nucleophilic addition reactions. The ester moiety enhances solubility in polar organic solvents while maintaining stability under standard bench conditions. This scaffold serves as a key intermediate for bioactive molecule synthesis.

Application

Methyl (E)-3-(3-formyl-4-hydroxyphenyl)acrylate serves as a versatile building block for the synthesis of bioactive heterocycles and natural product analogs. The conjugated enal–ester system enables reliable Michael additions, aldol condensations, and transition-metal-catalyzed coupling reactions. The phenolic hydroxyl group provides a site for selective derivatization, while the aldehyde functionality supports reductive amination and oxime formation. Bench-stable and amenable to standard purification methods, it facilitates efficient access to complex scaffolds in medicinal chemistry and materials science applications.

General Information

  • CAS No. 417712-26-6
  • Cat. No. CS-0200423
  • Purity ≥97%
  • MDL No. MFCD22575202
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀O₄
  • Molecular Weight 206.19
  • Synonym(s) None
  • SMILES O=C(OC)/C=C/C1=CC=C(O)C(C=O)=C1

Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.3909
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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