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Structure of 41860-64-4
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4-Fluoro-2-iodo-1-nitrobenzene features a trifunctional aromatic core with electron-withdrawing nitro and iodine groups flanking a fluorine substituent. This configuration enables direct coupling in cross-coupling reactions, offering high reactivity under palladium catalysis. The molecule exhibits excellent stability under standard handling conditions and integrates readily into complex synthetic sequences requiring orthogonal functional group compatibility.
4-Fluoro-2-iodo-1-nitrobenzene serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of substituted aromatic systems. The ortho-iodo and fluoro groups provide complementary reactivity for sequential functionalization via palladium-catalyzed coupling and nucleophilic aromatic substitution. Its bench-stable nature and tolerance to diverse reaction conditions facilitate reliable use in multi-step syntheses of pharmaceutical intermediates and advanced materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: