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Structure of 41888-21-5
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2-Oxopiperidine-3-carboxylic acid features a rigid, electron-deficient piperidine core with a strategically positioned carboxylic acid and ketone group. This bifunctional scaffold integrates readily into peptidomimetic architectures, serving as a key building block for constrained bioactive molecules in medicinal chemistry. The molecule exhibits enhanced metabolic stability and favorable conformational bias.
2-Oxopiperidine-3-carboxylic acid serves as a key scaffold for the synthesis of bioactive heterocycles and peptidomimetics. Its α,β-unsaturated carbonyl system enables efficient Michael additions and nucleophilic conjugate reactions, while the carboxylic acid facilitates amide coupling and derivatization. The compound exhibits good bench stability and is compatible with standard synthetic protocols, making it a practical building block for medicinal chemistry campaigns targeting CNS modulators and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: