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Structure of 4210-32-6
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4-(tert-Butyl)benzonitrile features a sterically hindered tert-butyl group para to a nitrile-bearing aromatic ring, delivering enhanced solubility and stability. This combination enables efficient integration into pharmaceutical intermediates and functional materials where electron-withdrawing nitrile functionality is required without compromising bulk tolerance or process robustness under standard conditions.
4-(tert-Butyl)benzonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aryl nitriles and heterocyclic scaffolds. Its tert-butyl group provides steric bulk and enhanced bench stability, while the nitrile moiety offers reliable reactivity in nucleophilic additions, reductions, and cyclizations. The compound exhibits excellent functional group tolerance and facilitates straightforward purification, making it well-suited for medicinal chemistry lead optimization and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: