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Structure of 42123-33-1
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3-Hydroxy-2-nitrobenzaldehyde features a strategically positioned hydroxyl group adjacent to an electron-deficient nitro-substituted aromatic ring, enabling unique reactivity in transition metal-catalyzed couplings. This ortho-hydroxy nitroaromatic aldehyde integrates readily into complex molecular architectures, offering enhanced solubility and stability under standard bench conditions.
3-Hydroxy-2-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized heterocycles via condensation and cyclization reactions. Its ortho-hydroxyl and nitro groups facilitate chelation and directed metalation, enhancing regioselectivity in electrophilic substitutions. The aldehyde functionality supports facile derivatization through imine formation, reductive amination, or oxidative transformations. Bench-stable and readily purified by recrystallization, it functions as a reliable scaffold for synthesizing bioactive molecules and advanced ligands.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: