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CS-W001157 4
Total: USD 88.00

5,6,7,8-Tetrahydro-1-naphthalenecarboxylic acid

  • CAS No. 4242-18-6

  • Cat. No. CS-D0710
  • Purity≥95%
  • MDL No.MFCD01464030
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-Tetrahydro-1-naphthalenecarboxylic acid|CS-D0710

Structure of 4242-18-6

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Description

This tetrahydro-1-naphthalenecarboxylic acid features a saturated naphthalene core with a carboxylic acid group at the 1-position, offering enhanced stability and solubility in polar solvents. The fully reduced ring system imparts reduced aromaticity, enabling selective functionalization in synthetic sequences. This structural motif serves as a key intermediate in medicinal chemistry and materials science, particularly for building bioactive scaffolds and conjugated polymers.

Application

5,6,7,8-Tetrahydro-1-naphthalenecarboxylic acid serves as a versatile building block in medicinal chemistry and synthetic organic research. Its saturated bicyclic core provides enhanced metabolic stability while maintaining favorable lipophilic character. The carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation, facilitating incorporation into bioactive molecules and heterocyclic scaffolds. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling reactions and multistep syntheses.

General Information

  • CAS No. 4242-18-6
  • Cat. No. CS-D0710
  • Purity ≥95%
  • MDL No. MFCD01464030
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O₂
  • Molecular Weight 176.22
  • Synonym(s) 5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid
  • SMILES OC(C1=CC=CC2=C1CCCC2)=O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2636
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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