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Structure of 4242-18-6
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This tetrahydro-1-naphthalenecarboxylic acid features a saturated naphthalene core with a carboxylic acid group at the 1-position, offering enhanced stability and solubility in polar solvents. The fully reduced ring system imparts reduced aromaticity, enabling selective functionalization in synthetic sequences. This structural motif serves as a key intermediate in medicinal chemistry and materials science, particularly for building bioactive scaffolds and conjugated polymers.
5,6,7,8-Tetrahydro-1-naphthalenecarboxylic acid serves as a versatile building block in medicinal chemistry and synthetic organic research. Its saturated bicyclic core provides enhanced metabolic stability while maintaining favorable lipophilic character. The carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation, facilitating incorporation into bioactive molecules and heterocyclic scaffolds. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling reactions and multistep syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: