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Structure of 42436-86-2
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2-Phenylcyclobutan-1-one features a rigid, strained cyclobutanone ring fused to a phenyl group, delivering enhanced reactivity at the carbonyl site. This structure supports efficient conjugate additions and enables direct functionalization in synthetic routes. The compound serves as a key scaffold for constructing complex polycyclic frameworks in medicinal chemistry and natural product synthesis.
2-Phenylcyclobutan-1-one serves as a versatile building block in synthetic organic chemistry, enabling the construction of complex carbocyclic and heterocyclic scaffolds. Its ketone functionality supports standard transformations such as nucleophilic addition, reduction, and enolization, while the adjacent phenyl group enhances stability and facilitates downstream functionalization. The compound exhibits bench stability and compatibility with common reaction conditions, making it valuable for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: