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Structure of 42466-67-1
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(E)-Ethyl 2-cyano-3-ethoxyacrylate is a bench-stable, electron-deficient acrylate ester featuring a conjugated cyano and ethoxy group. This configuration enables efficient Michael addition reactions and Diels-Alder cycloadditions under mild conditions. The (E)-geometry ensures predictable stereochemistry in synthetic transformations. It serves as a key building block for heterocyclic compounds and functionalized polymers.
(E)-Ethyl 2-cyano-3-ethoxyacrylate serves as a versatile Michael acceptor and key building block in heterocyclic synthesis, enabling efficient access to pyrroles, pyridines, and other nitrogen-containing scaffolds via condensation and cycloaddition reactions. Its well-defined (E)-configuration ensures predictable stereochemical outcomes, while the cyano and ester groups offer orthogonal reactivity for sequential transformations. Bench-stable and readily purified by flash chromatography, it functions effectively in multistep syntheses requiring high functional group tolerance and reproducible yields.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS08
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Signal Word : Danger
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UN#: 3335
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H334-H335
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Precautionary Statements : P261-P264-P270-P271-P272-P280-P285-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: