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Structure of 4265-16-1
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Benzo[b]furan-2-carboxaldehyde features a fused heterocyclic core with an aldehyde handle at the 2-position, enabling direct incorporation into Suzuki-Miyaura couplings and nucleophilic addition reactions. The electron-deficient aromatic system enhances reactivity in transition-metal-catalyzed transformations, while the bench-stable aldehyde group permits handling under standard conditions. This scaffold serves as a key building block for bioactive molecules and functional materials.
Benzo[b]furan-2-carboxaldehyde serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the aldehyde position for subsequent transformations such as reductive amination, Grignard addition, or cyanide conjugation. Its fused heterocyclic architecture provides enhanced stability and orthogonal reactivity, facilitating incorporation into pharmaceutical intermediates and agrochemical scaffolds. The compound exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: