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Structure of 426831-32-5
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(5-Fluoro-2-methoxyphenyl)methanol features a fluorinated aromatic core with a methoxy group at the ortho position and a primary alcohol at the benzylic site. This combination imparts enhanced metabolic stability and favorable lipophilicity, making it a valuable building block in medicinal chemistry for accessing bioactive compounds through direct functionalization or coupling reactions.
(5-Fluoro-2-methoxyphenyl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated aromatic scaffolds. Its benzyl alcohol functionality facilitates direct derivatization via oxidation, etherification, or esterification, while the ortho-methoxy and meta-fluoro substituents provide enhanced metabolic stability and modulated electronic properties. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: