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Structure of 42881-66-3
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4-Bromo-6-methoxyquinoline is a heterocyclic compound featuring a quinoline core with bromine and methoxy substituents at the 4- and 6-positions, respectively. This electron-deficient scaffold enables efficient coupling in palladium-catalyzed cross-coupling reactions. The methoxy group enhances solubility and modulates electronic properties, while the bromine serves as a reliable handle for further functionalization. This molecule exhibits bench-stable handling characteristics and integrates readily into synthetic sequences requiring directed metalation or transition-metal-mediated transformations.
4-Bromo-6-methoxyquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity. The methoxy group enhances solubility and modulates electronic properties, while the quinoline scaffold provides a rigid, planar framework suitable for constructing heterocyclic APIs and functional organic semiconductors. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P305+P351+P338-P330-P501
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Lot numbers can be found on the outside label of a product: