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Structure of 43038-45-5
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1-Naphthohydrazide is a bench-stable, electron-rich hydrazide derivative featuring a naphthalene core that enables facile integration into heterocyclic synthesis. This compound serves as a key scaffold for constructing bioactive nitrogen-containing systems, particularly in the development of pharmacophores and ligands for transition metal catalysis.
1-Naphthohydrazide serves as a versatile building block in heterocyclic synthesis, enabling efficient access to quinazoline, pyrazole, and triazole derivatives via condensation and cyclization reactions. Its naphthalene framework imparts enhanced stability and facilitates purification by crystallization, while the hydrazide functionality exhibits reliable reactivity with aldehydes, ketones, and activated esters under mild conditions. Functions effectively in both solution-phase and solid-phase synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: