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CS-W001157 4
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3-Trimethylsilyl-2-oxazolidinone

  • CAS No. 43112-38-5

  • Cat. No. CS-0204861
  • Purity≥98%
  • MDL No.MFCD00010197

*For research and further manufacturing use only, not for direct human use.

3-Trimethylsilyl-2-oxazolidinone|CS-0204861

Structure of 43112-38-5

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General Information

  • CAS No. 43112-38-5
  • Cat. No. CS-0204861
  • Purity ≥98%
  • MDL No. MFCD00010197
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂Si
  • Molecular Weight 159.26
  • Synonym(s) Trimethyl(2-oxo-3-oxazolidinyl)silane
  • SMILES O=C1OCCN1[Si](C)(C)C

Description

3-Trimethylsilyl-2-oxazolidinone serves as a robust silylating agent with enhanced stability and ease of handling. This bench-stable reagent features a reactive oxazolidinone ring flanked by a trimethylsilyl group, enabling efficient protection of hydroxyl and amine functionalities under mild conditions.

Synthesis

  • Route1
    • In-stock
      Oxazolidin-2-one|CS-W007548
      497-25-6
    • null|null
      75-77-4
    • ~90%
    • In-stock
      3-Trimethylsilyl-2-oxazolidinone|CS-0204861
      43112-38-5

    References

    • Aizpurua, Jesus Mari; Palomo, Claudio Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 7-8 p. 265 - 268
  • Route2
    • In-stock
      Oxazolidin-2-one|CS-W007548
      497-25-6
    • Trimethylsilyl Trichloroacetate|CS-0738698
      25436-07-1
    • ~91%
    • In-stock
      3-Trimethylsilyl-2-oxazolidinone|CS-0204861
      43112-38-5

    References

    • Renga, James M.; Pen-Chung, Wang Tetrahedron Letters, 1985 , vol. 26, # 9 p. 1175 - 1178

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P280-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   1.2735
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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