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CS-W001157 4
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3-(Methylsulfonyl)benzaldehyde

  • CAS No. 43114-43-8

  • Cat. No. CS-0045737
  • Purity≥96%
  • MDL No.MFCD11052329

*For research and further manufacturing use only, not for direct human use.

3-(Methylsulfonyl)benzaldehyde|CS-0045737

Structure of 43114-43-8

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General Information

  • CAS No. 43114-43-8
  • Cat. No. CS-0045737
  • Purity ≥96%
  • MDL No. MFCD11052329
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₃S
  • Molecular Weight None
  • Synonym(s) 3-methylsulfonylbenzaldehyde
  • SMILES CS(=O)(=O)C1=CC=CC(C=O)=C1

Description

3-(Methylsulfonyl)benzaldehyde features a para-methylsulfonyl group that imparts enhanced solubility and metabolic stability, while the aldehyde functionality enables direct incorporation into multistep syntheses. This bench-stable reagent streamlines access to functionalized aromatic scaffolds in medicinal chemistry and materials development.

Application

3-(Methylsulfonyl)benzaldehyde serves as a versatile building block in medicinal chemistry and process development, enabling efficient access to functionalized aromatic scaffolds. The methylsulfonyl group enhances solubility and metabolic stability, while the aldehyde functionality facilitates diverse transformations including reductive amination, Wittig reactions, and nucleophilic additions. Its bench-stable nature and compatibility with common protecting group strategies make it well-suited for multi-step synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.21
  • LogP   0.9026
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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