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Structure of 431888-57-2
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2-Chloro-4-(methoxycarbonyl)benzoic acid features a strategically positioned chloro group and ester-functionalized carboxylic acid, enabling direct integration into pharmaceutical intermediates. This electron-deficient aromatic scaffold facilitates efficient coupling reactions under standard conditions.
2-Chloro-4-(methoxycarbonyl)benzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other heterocyclic scaffolds. The ortho-chloro and ester functionalities offer complementary reactivity for palladium-catalyzed coupling and selective hydrolysis, respectively. Its bench-stable crystalline form facilitates handling and purification, while the carboxylic acid group allows direct derivatization or activation for amide bond formation in peptide-like architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: