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Structure of 433257-41-1
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1-Bromo-4-(trimethylsilyl)but-3-yn-2-one features a reactive alkyne tethered to a bromo-substituted ketone, enabling efficient copper-catalyzed coupling reactions. The trimethylsilyl group enhances stability and facilitates deprotection under mild conditions, streamlining synthetic access to functionalized alkynes in complex molecule assembly.
1-Bromo-4-(trimethylsilyl)but-3-yn-2-one serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to functionalized alkynyl motifs. The molecule combines a reactive bromide with a silyl-protected alkyne and an α-keto carbonyl group, offering orthogonal reactivity for sequential transformations. Its bench-stable nature and compatibility with palladium- and copper-mediated cross-couplings facilitate streamlined synthesis of complex intermediates for medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS08
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H227-H314-H317-H318-H334-H335
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Precautionary Statements : P210-P260-P264-P271-P272-P280-P285-P301+P330+P331-P302+P352-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: