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CS-W001157 4
Total: USD 88.00

(2-Formylthiophen-3-yl)boronic acid

  • CAS No. 4347-31-3

  • Cat. No. CS-0043939
  • Purity≥97%
  • MDL No.MFCD01075678
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2-Formylthiophen-3-yl)boronic acid|CS-0043939

Structure of 4347-31-3

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Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering functionalized thiophene scaffolds with high efficiency. The aldehyde group enables downstream derivatization via condensation or reductive amination, enhancing synthetic versatility in pharmaceutical and materials chemistry applications.

Application

(2-Formylthiophen-3-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biologically relevant thiophene-containing scaffolds. The pendant aldehyde group offers orthogonal functionality for downstream derivatization via reductive amination or condensation reactions. Its stability under standard reaction conditions and compatibility with common protecting groups facilitate streamlined synthesis in medicinal chemistry and materials science applications.

General Information

  • CAS No. 4347-31-3
  • Cat. No. CS-0043939
  • Purity ≥97%
  • MDL No. MFCD01075678
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BO₃S
  • Molecular Weight 155.97
  • Synonym(s) 2-Formylthiophene-3-boronic acid
  • SMILES OB(O)C1=C(SC=C1)C=O

Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.7596
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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