(R)-1-Boc- 3-ethyl-piperazine

Name: (R)-1-Boc- 3-ethyl-piperazine
Brand: ChemScene
Availability: InStock
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CAS No. 438050-08-9
Cat. No. CS-W008682
Purity≥97%
MDL No.MFCD07772111

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-1-Boc- 3-ethyl-piperazine|CS-W008682

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Description

(R)-1-Boc-3-ethyl-piperazine is a stereochemically defined piperazine derivative featuring a Boc-protected nitrogen and an ethyl substituent at the 3-position. This bench-stable, moisture-tolerant building block integrates readily into complex molecular architectures, enabling efficient access to chiral pharmacophores in medicinal chemistry and target-oriented synthesis.

Application

(R)-1-Boc-3-ethylpiperazine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amine functionalization and coupling reactions. Its Boc group provides excellent bench stability and orthogonal deprotection compatibility, while the piperazine core offers favorable solubility and metabolic stability in downstream applications. The (R)-stereochemistry ensures predictable stereochemical control in target molecule construction.

General Information

CAS No. 438050-08-9
Cat. No. CS-W008682
Purity ≥97%
MDL No. MFCD07772111
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₂₂N₂O₂
Molecular Weight 214.30
Synonym(s) (R)-tert-butyl 3-ethylpiperazine-1-carboxylate
SMILES O=C(OC(C)(C)C)N1C[C@@H](CC)NCC1

Computational Chemistry Data

TPSA 41.57
LogP 1.6053
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-Boc- 3-ethyl-piperazine

CAS No. 438050-08-9

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