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Structure of 439280-18-9
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3-Fluoro-5-methoxybenzonitrile features a fluorine atom at the meta position and a methoxy group at the para position relative to the nitrile, creating a uniquely electron-deficient aromatic scaffold. This configuration enhances reactivity in cross-coupling processes while maintaining bench-stable handling characteristics. The molecule integrates readily into pharmaceutical intermediates and functional materials where directional electronic modulation is critical.
3-Fluoro-5-methoxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the aromatic ring via palladium-catalyzed cross-coupling reactions. The nitrile group provides a robust handle for downstream transformations, while the fluorine and methoxy substituents offer favorable electronic and metabolic stability. This compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: