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CS-W001157 4
Total: USD 88.00

O-Succinimidyl-1,3-dimethylpropyleneuronium tetrafluoroborate

  • CAS No. 443305-34-8

  • Cat. No. CS-0209022
  • Purity≥98%
  • MDL No.MFCD08274621
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

O-Succinimidyl-1,3-dimethylpropyleneuronium tetrafluoroborate|CS-0209022

Structure of 443305-34-8

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Description

This activated ester features a dimethylpropylene linker that enhances solubility and stability in aqueous and organic media. It facilitates efficient coupling of carboxylic acids to primary amines under mild conditions, delivering robust amide bond formation with minimal racemization. Ideal for bioconjugation and peptide synthesis workflows requiring rapid, high-yield ligation.

Application

O-Succinimidyl-1,3-dimethylpropyleneuronium tetrafluoroborate serves as a robust activated ester reagent for amide bond formation, enabling efficient coupling of carboxylic acids with amines under mild conditions. Its bench-stable nature and low tendency to hydrolyze facilitate reliable conjugation workflows. The tetrafluoroborate counterion enhances solubility in organic solvents, improving reaction homogeneity and simplifying purification. This reagent functions effectively in peptide synthesis, protein labeling, and bioconjugation applications where high yield and functional group tolerance are critical.

General Information

  • CAS No. 443305-34-8
  • Cat. No. CS-0209022
  • Purity ≥98%
  • MDL No. MFCD08274621
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆BF₄N₃O₃
  • Molecular Weight 313.06
  • Synonym(s) 2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3,4,5,6-tetrahydro-1,3-dimethylpyrimidinium tetrafluoroborate
  • SMILES O=C(N1[O+]=C(N2)NC(C)C2CC)CCC1=O.F[B-](F)(F)F

Computational Chemistry Data

  • TPSA   72.74
  • LogP   1.366
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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