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Structure of 443776-76-9
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This boronate-functionalized benzyl alcohol integrates seamlessly into Suzuki-Miyaura coupling reactions, offering high stability and compatibility with diverse reaction conditions. The tetramethyl-1,3,2-dioxaborolane moiety ensures reliable performance under standard bench protocols, while the pendant hydroxyl group enables further derivatization or incorporation into complex molecular architectures.
(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol serves as a versatile boronate building block in palladium-catalyzed cross-coupling reactions. Its stable dioxaborolane group enables efficient Suzuki-Miyaura coupling with aryl and heteroaryl halides, facilitating the construction of biaryl and extended conjugated scaffolds. The pendant benzyl alcohol functionality offers a handle for further derivatization or incorporation into pharmaceutical intermediates, while the tetramethyl substitution enhances bench stability and minimizes protodeboronation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: