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Structure of 4441-12-7
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Tri(4-morpholinyl)phosphine oxide features a phosphine oxide core bearing three 4-morpholinyl groups, delivering enhanced solubility and stability in polar solvents. This electron-rich ligand integrates readily into catalytic systems, particularly in transition-metal-mediated transformations, where its steric profile and donor strength promote efficient reaction pathways under mild conditions.
Tri(4-morpholinyl)phosphine oxide serves as a robust, bench-stable ligand in transition metal-catalyzed cross-coupling reactions, particularly in palladium-mediated processes. Its electron-rich morpholine groups enhance phosphine donor strength while improving air stability compared to triarylphosphines. The oxide functionality further stabilizes the phosphine center, enabling reliable performance in demanding synthetic transformations and facilitating purification due to its polar character.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: