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CS-W001157 4
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Cycloheptylmethanol

  • CAS No. 4448-75-3

  • Cat. No. CS-0144557
  • Molecule weight128.21
  • Purity≥96%
  • MDL No.MFCD00004154

*For research and further manufacturing use only, not for direct human use.

Cycloheptylmethanol|CS-0144557

Structure of 4448-75-3

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General Information

  • CAS No. 4448-75-3
  • Cat. No. CS-0144557
  • Purity ≥96%
  • MDL No. MFCD00004154
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O
  • Molecular Weight 128.21
  • Synonym(s) Cycloheptanemethanol
  • SMILES OCC1CCCCCC1

Description

Cycloheptylmethanol offers a rigid, medium-ring scaffold with a primary alcohol handle for functionalization. This bench-stable, moisture-tolerant compound integrates readily into synthetic sequences requiring steric bulk and controlled reactivity.

Application

Cycloheptylmethanol serves as a versatile synthetic building block in organic synthesis, offering a stable, bench-friendly primary alcohol functionality. Its cycloheptyl moiety provides steric bulk and hydrophobic character useful in medicinal chemistry scaffolds. The compound facilitates efficient derivatization via standard alcohol transformations—such as oxidation to aldehydes or carboxylic acids, esterification, and protection—enabling access to diverse functionalized intermediates with high reproducibility in routine laboratory workflows.

Synthesis

  • Route1

    References

    • Vincek, William C.; Aldrich, Constance S.; Borchardt, Ronald T.; Grunewald, Gary L. Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 7 - 12
  • Route2
    • null|null
      78371-04-7
    • ~98%
    • In-stock
      Cycloheptylmethanol|CS-0144557
      4448-75-3
    • null|null
      620-05-3

    References

    • Olah, George A.; Husain, Altaf; Singh, Brij P.; Mehrotra, Ashok K. Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3667 - 3672
  • Route3
    • null|null
      78371-03-6
    • ~99%
    • In-stock
      Cycloheptylmethanol|CS-0144557
      4448-75-3
    • null|null
      620-05-3

    References

    • Olah, George A.; Husain, Altaf; Singh, Brij P.; Mehrotra, Ashok K. Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3667 - 3672 Title/Abstract Full Text View citing articles Show Details Olah, George A.; Husain, Altaf; Gupta, B. G. Balaram; Narang, Subhash C. Angewandte Chemie, 1981 , vol. 93, # 8 p. 705 - 706

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.9491
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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