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Structure of 445-28-3
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2-Fluorobenzamide delivers a fluorinated aromatic scaffold with enhanced metabolic stability and improved membrane permeability. The ortho-fluoro substitution modulates electronic properties, enabling precise tuning of reactivity in pharmaceutical intermediates. This bench-stable amide integrates seamlessly into complex synthesis pathways, offering reliable functionality under standard conditions.
2-Fluorobenzamide serves as a versatile building block in medicinal chemistry, offering a fluorinated aromatic scaffold with predictable reactivity. The amide group enables direct functionalization or coupling reactions, while the ortho-fluoro substituent provides enhanced metabolic stability and modulates electronic properties. Its bench-stable nature facilitates straightforward handling and purification, making it well-suited for use in standard amide bond formations, Suzuki couplings, and heterocycle synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: