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Structure of 445041-29-2
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2,5-Dichloroquinazoline features a rigid heteroaromatic core with two chlorine substituents positioned at electron-rich sites, enabling selective electrophilic functionalization. This configuration supports efficient coupling reactions in medicinal chemistry and materials synthesis under standard conditions.
2,5-Dichloroquinazoline serves as a versatile building block in medicinal chemistry, enabling efficient construction of quinazoline-based scaffolds through palladium-catalyzed cross-coupling reactions. Its orthogonal reactivity allows selective functionalization at C2 and C5 positions, facilitating the synthesis of biologically active heterocycles with high regiocontrol. The compound exhibits excellent bench stability and is readily purified by flash chromatography, making it well-suited for scale-up and multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: