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Structure of 445264-60-8
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5-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine features a boronate ester group that enables efficient Suzuki-Miyaura cross-coupling under mild conditions. The electron-rich pyridine core enhances reactivity, while the tetramethyl-substituted dioxaborolane imparts stability and moisture tolerance. This compound integrates readily into complex molecular architectures during late-stage functionalization.
5-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables robust coupling under mild conditions, while the pyridine core provides a stable heterocyclic scaffold with enhanced solubility and functional group tolerance. Bench-stable and readily purified by flash chromatography, it facilitates efficient construction of biaryl and heteroaryl architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: