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Structure of 445303-10-6
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This boronate ester features a 3-chloro-4-methylphenyl group attached to a tetramethyl-substituted dioxaborolane ring, offering enhanced stability and moisture tolerance. It integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, enabling efficient C–C bond formation with aryl halides and triflates. The sterically protected boron center resists protodeboronation, ensuring high functional group compatibility in complex molecule synthesis.
2-(3-Chloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a robust boron building block for Suzuki-Miyaura cross-coupling reactions. Its stability under ambient conditions and tolerance to diverse functional groups enable reliable C–C bond formation in medicinal chemistry and materials synthesis. The tetramethyl substitution enhances shelf life and simplifies purification, making it ideal for high-throughput applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: