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CS-W001157 4
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(Methoxymethyl)diphenylphosphine oxide

  • CAS No. 4455-77-0

  • Cat. No. CS-0095780
  • Molecule weight246.24
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(Methoxymethyl)diphenylphosphine oxide|CS-0095780

Structure of 4455-77-0

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General Information

  • CAS No. 4455-77-0
  • Cat. No. CS-0095780
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅O₂P
  • Molecular Weight 246.24
  • Synonym(s) Diphenyl(methoxymethyl)phosphine Oxide
  • SMILES COCP(C1=CC=CC=C1)(C2=CC=CC=C2)=O

Description

(Methoxymethyl)diphenylphosphine oxide features a phosphine oxide moiety flanked by two phenyl rings and a methoxymethyl group, delivering enhanced stability and solubility in polar aprotic solvents. This combination enables efficient coupling reactions under mild conditions, with the methoxymethyl substituent offering controlled reactivity and ease of removal when required.

Synthesis

  • Route1
    • null|null
      1079-66-9
    • In-stock
      Methoxyacetic acid|CS-W020123
      625-45-6
    • ~%
    • In-stock
      (Methoxymethyl)diphenylphosphine oxide|CS-0095780
      4455-77-0

    References

    • STRAITMARK HOLDING AG; BURCK, Sebastian, R., W.; NOTTÉ, Patrick Patent: WO2013/17564 A2, 2013 ; Location in patent: Page/Page column 48; 49 ;
  • Route2
    • null|null
      107-30-2
    • null|null
      603-35-0
    • ~72%
    • In-stock
      (Methoxymethyl)diphenylphosphine oxide|CS-0095780
      4455-77-0

    References

    • Morita, Hiroyuki; Tashiro, Shintaro; Takeda, Masahiro; Fujimori, Ken; Yamada, Nobuhiko; Chanmiya Sheikh; Kawaguchi, Hiroyuki Tetrahedron, 2008 , vol. 64, # 16 p. 3589 - 3595
  • Route3

    References

    • STRAITMARK HOLDING AG; BURCK, Sebastian R., W.; COGELS, Samuel, Corentin; NOTTE, Patrick Patent: WO2012/98255 A1, 2012 ; Location in patent: Page/Page column 44 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.6044
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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