Methyl trityl-L-serinate

Name: Methyl trityl-L-serinate
Brand: ChemScene
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CAS No. 4465-44-5
Cat. No. CS-0112559
Purity≥95%
MDL No.MFCD00192570

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 4465-44-5

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Description

Methyl trityl-L-serinate serves as a protected amino acid derivative, featuring a trityl group at the amine and methyl ester at the carboxylate. This configuration enables stable incorporation into peptide synthesis workflows, where the trityl moiety offers robust protection against racemization and facilitates selective deprotection under mild acidic conditions.

Application

Methyl trityl-L-serinate serves as a robust chiral protecting group for amino acids, enabling efficient peptide synthesis through orthogonal deprotection. Its trityl moiety provides excellent solubility and stability under standard reaction conditions, while the methyl ester facilitates straightforward hydrolysis. The compound functions reliably in solid-phase and solution-phase workflows, offering high fidelity during chain elongation and simplifying purification of intermediates.

General Information

CAS No. 4465-44-5
Cat. No. CS-0112559
Purity ≥95%
MDL No. MFCD00192570
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₃NO₃
Molecular Weight 361.43
Synonym(s) Trt-Ser-OMe
SMILES OC[C@H](NC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(OC)=O

Computational Chemistry Data

TPSA 58.56
LogP 3.102
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Serine and derivatives

Life Science Amino Acids and their Derivatives N-protected amino acid

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Methyl trityl-L-serinate

CAS No. 4465-44-5

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