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Structure of 446831-28-3
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3-(Piperazin-1-yl)benzoic acid features a piperazine ring tethered to a benzene core, delivering enhanced solubility and hydrogen-bonding capacity. The carboxylic acid group enables direct conjugation or derivatization, making this scaffold valuable in medicinal chemistry for optimizing pharmacokinetic profiles and target engagement.
3-(Piperazin-1-yl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and drug candidates. Its piperazine moiety offers enhanced solubility and hydrogen-bonding capacity, while the carboxylic acid group facilitates straightforward derivatization via amide, ester, or amidation reactions. The compound exhibits good bench stability and is compatible with standard synthetic protocols, making it a practical choice for lead optimization and scaffold diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: