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Structure of 447-60-9
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2-(Trifluoromethyl)benzonitrile features a trifluoromethyl group flanking a nitrile moiety on a benzene ring, delivering high electron deficiency and enhanced metabolic stability. This configuration enables efficient coupling in cross-coupling reactions and serves as a key building block in pharmaceutical and agrochemical synthesis.
2-(Trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient introduction of both trifluoromethyl and nitrile functionalities into complex molecular architectures. Its stability, compatibility with standard coupling reactions, and predictable reactivity under nucleophilic and electrophilic conditions make it a reliable scaffold for constructing bioactive heterocycles and functionalized aromatic systems.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H227-H301+H311+H331-H315-H319
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P361-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: