Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,6-Dichloro-2-methylsulfonylpyrimidine

  • CAS No. 4489-34-3

  • Cat. No. CS-D0908
  • Purity≥98%
  • MDL No.MFCD00672147
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloro-2-methylsulfonylpyrimidine|CS-D0908

Structure of 4489-34-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

4,6-Dichloro-2-methylsulfonylpyrimidine features a pyrimidine core bearing two chlorine substituents at the 4 and 6 positions and a methylsulfonyl group at C2, delivering high reactivity in nucleophilic substitution. This electron-deficient scaffold enables efficient coupling with amines and thiols under mild conditions, making it ideal for constructing bioactive heterocycles in medicinal chemistry and chemical biology applications.

Application

4,6-Dichloro-2-methylsulfonylpyrimidine serves as a versatile pyrimidine-based building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. The dichloro substituents enable selective nucleophilic substitution under mild conditions, while the methylsulfonyl group enhances solubility and provides a handle for further derivatization. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient construction of complex scaffolds in medicinal chemistry and process development workflows.

General Information

  • CAS No. 4489-34-3
  • Cat. No. CS-D0908
  • Purity ≥98%
  • MDL No. MFCD00672147
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Cl₂N₂O₂S
  • Molecular Weight 227.07
  • Synonym(s) 4,6-Dichloro-2-(Methylsulfonyl)pyrimidine
  • SMILES O=S(C1=NC(Cl)=CC(Cl)=N1)(C)=O

Computational Chemistry Data

  • TPSA   59.92
  • LogP   1.1869
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4,6-Dichloro-2-methylsulfonylpyrimidine sigma4,6-Dichloro-2-methylsulfonylpyrimidine manufacturer4,6-Dichloro-2-methylsulfonylpyrimidine price4,6-Dichloro-2-methylsulfonylpyrimidine structure4,6-Dichloro-2-methylsulfonylpyrimidine SDSbuy 4,6-Dichloro-2-methylsulfonylpyrimidine4,6-Dichloro-2-methylsulfonylpyrimidine supplier4,6-Dichloro-2-methylsulfonylpyrimidine uses4,6-Dichloro-2-methylsulfonylpyrimidine molecular weightprice of 4,6-Dichloro-2-methylsulfonylpyrimidine4,6-Dichloro-2-methylsulfonylpyrimidine chemical name formula of 4,6-Dichloro-2-methylsulfonylpyrimidine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label