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Structure of 4489-34-3
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4,6-Dichloro-2-methylsulfonylpyrimidine features a pyrimidine core bearing two chlorine substituents at the 4 and 6 positions and a methylsulfonyl group at C2, delivering high reactivity in nucleophilic substitution. This electron-deficient scaffold enables efficient coupling with amines and thiols under mild conditions, making it ideal for constructing bioactive heterocycles in medicinal chemistry and chemical biology applications.
4,6-Dichloro-2-methylsulfonylpyrimidine serves as a versatile pyrimidine-based building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. The dichloro substituents enable selective nucleophilic substitution under mild conditions, while the methylsulfonyl group enhances solubility and provides a handle for further derivatization. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient construction of complex scaffolds in medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: