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Structure of 450-83-9
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4-Fluoro-2-methoxybenzaldehyde features a fluorine atom at the para position and a methoxy group at the ortho position relative to the aldehyde, delivering enhanced electron withdrawal and steric influence. This combination enables selective reactivity in cross-coupling and condensation reactions, particularly valuable in synthesizing bioactive heterocycles and pharmaceutical intermediates under standard conditions.
4-Fluoro-2-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering a strategically positioned aldehyde group for reductive amination, Grignard addition, or Wittig reactions. The ortho-methoxy and para-fluoro substituents provide enhanced electronic tuning and metabolic stability, while the compound exhibits excellent bench stability and facilitates straightforward purification via flash chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: