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CS-W001157 4
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Sodium α-ketoisocaproate

  • CAS No. 4502-00-5

  • Cat. No. CS-W018103
  • Purity≥98%
  • MDL No.MFCD00064193
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Sodium α-ketoisocaproate|CS-W018103

Structure of 4502-00-5

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Description

Sodium 4-methyl-2-oxovalerate (CAS 4502-00-5) drives insulin secretion through leucine-derived metabolic flux, undergoes oxidative degradation to acetyl-CoA and acetoacetic acid, and regenerates leucine via transamination with glutamate, yielding α-ketoglutarate.

Application

Sodium 4-methyl-2-oxovalerate (CAS 4502-00-5) enables precise quantification of branched-chain keto acids in cellular extracts through HPLC-fluorescence detection, acting as a critical reference standard for metabolic profiling. This method delivers high sensitivity and reproducibility. Researchers rely on it to track key intermediates in amino acid catabolism with minimal background interference.

General Information

  • CAS No. 4502-00-5
  • Cat. No. CS-W018103
  • Purity ≥98%
  • MDL No. MFCD00064193
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉NaO₃
  • Molecular Weight 152.12
  • Synonym(s) Sodium 4-methyl-2-oxopentanoate; 2-Ketoisocaproic acid (sodium salt)
  • SMILES [Na].O=C(O)C(=O)CC(C)C

Computational Chemistry Data

  • TPSA   54.37
  • LogP   0.0377
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P317

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