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Structure of 450412-21-2
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3-Bromo-2-iodobenzonitrile features a dual halogenated aromatic core with complementary reactivity for cross-coupling transformations. The ortho-bromine and iodine positions enable sequential functionalization, while the nitrile group provides a polar handle for downstream derivatization. This molecule integrates readily into complex scaffolds under palladium-catalyzed conditions.
3-Bromo-2-iodobenzonitrile serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The ortho-halogen substitution pattern provides predictable reactivity in Suzuki, Stille, and Negishi couplings, while the nitrile group offers compatibility with various functionalizations. Bench-stable and readily purified by recrystallization, it facilitates streamlined synthesis of complex aromatic architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501
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Lot numbers can be found on the outside label of a product: