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CS-W001157 4
Total: USD 88.00

tert-Butyl 2-amino-2-methylpropanoate

  • CAS No. 4512-32-7

  • Cat. No. CS-0040411
  • Molecule weight159.23
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-amino-2-methylpropanoate|CS-0040411

Structure of 4512-32-7

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General Information

  • CAS No. 4512-32-7
  • Cat. No. CS-0040411
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO₂
  • Molecular Weight 159.23
  • Synonym(s) 2-amino-2-methylpropionic acid tert-butyl ester
  • SMILES NC(C)(C)C(OC(C)(C)C)=O

Synthesis

  • Route1
    • Tert-butyl 2-(benzyloxycarbonylamino)-2-methylpropanoate|CS-0747005
      4512-31-6
    • ~99%
    • tert-Butyl 2-amino-2-methylpropanoate|CS-0040411
      4512-32-7

    References

    • Ceccacci, Francesca; Mancini, Giovanna; Rossi, Paola; Scrimin, Paolo; Sorrenti, Alessandro; Tecilla, Paolo Chemical Communications, 2013 , vol. 49, # 86 p. 10133 - 10135
  • Route2
    • null|null
      1355158-73-4
    • ~%
    • tert-Butyl 2-amino-2-methylpropanoate|CS-0040411
      4512-32-7

    References

    • MERCK SERONO S.A.; BOMBRUN, Agnes; QUATTROPANI, Anna; GONZALEZ, Jerome; DORBAIS, Jerome; KNIGHT, Chris; BAKER-GLENN, Charles Patent: WO2012/4287 A1, 2012 ; Location in patent: Page/Page column 77 ; WO 2012/004287 A1
  • Route3
    • null|null
      540-88-5
    • α-Aminoisobutyric acid|CS-0229297
      62-57-7
    • ~53%
    • tert-Butyl 2-amino-2-methylpropanoate|CS-0040411
      4512-32-7

    References

    • Bavetsias, Vassilios; Jackman, Ann L.; Marriott, Jonathan H.; Kimbell, Rosemary; Gibson, William; Boyle, F. Thomas; Bisset, Graham M. F. Journal of Medicinal Chemistry, 1997 , vol. 40, # 10 p. 1495 - 1510

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.0654
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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