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Structure of 4526-07-2
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1,4-Bis(trimethylsilyl)buta-1,3-diyne serves as a stable, bench-ready building block for transition-metal-catalyzed couplings, enabling efficient access to conjugated enynes and substituted alkynes. Its dual trimethylsilyl groups enhance solubility and facilitate purification, while maintaining high functional group tolerance in Sonogashira, Glaser, and Cadiot-Chodkiewicz reactions. This reagent functions reliably in multi-step syntheses requiring selective alkyne incorporation and is particularly valuable in the construction of complex scaffolds for natural product and medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H228
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Precautionary Statements : P210-P240-P241-P280-P370+P378
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Lot numbers can be found on the outside label of a product: