Lot numbers can be found on the outside label of a product:
2,4,6-Trimethylbenzenesulfonamide
-
CAS No. 4543-58-2
- Cat. No. CS-0186497
- Purity≥97%
- MDL No.MFCD00463245
*For research and further manufacturing use only, not for direct human use.
Structure of 4543-58-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 4543-58-2
- Cat. No. CS-0186497
- Purity ≥97%
- MDL No. MFCD00463245
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₃NO₂S
- Molecular Weight 199.27
- Synonym(s) Benzenesulfonamide, 2,4,6-trimethyl- (9CI)
- SMILES CC1=CC(=C(C(=C1)C)S(=O)(=O)N)C
Description
2,4,6-Trimethylbenzenesulfonamide features a sterically hindered aromatic core with a sulfonamide group, offering enhanced stability and resistance to hydrolysis. The methyl substituents provide electron-donating effects and improve solubility in organic solvents. This compound serves as a robust scaffold for pharmaceutical intermediates and catalyst design.
Application
2,4,6-Trimethylbenzenesulfonamide serves as a robust sulfonamide building block in synthetic organic chemistry, offering enhanced stability and solubility due to its sterically hindered aryl core. Its tertiary sulfonamide functionality enables reliable coupling reactions and acts as a versatile handle in medicinal chemistry applications, particularly in the construction of kinase inhibitors and other bioactive scaffolds. The molecule exhibits excellent bench stability, facilitating straightforward handling and purification in standard laboratory workflows.
Synthesis
-
Route1
-
In-stock
773-64-8 - ~10%
-
In-stock
4543-58-2
References
-
Hayashi, Tamio; Kawai, Masahiro; Tokunaga, Norihito Angewandte Chemie - International Edition, 2004 , vol. 43, # 45 p. 6125 - 6128
-
-
Route2
-
161452-12-6 - ~94%
-
In-stock
4543-58-2
References
-
Mahalingam; Wu, Xiongyu; Wan, Yiqian; Alterman, Mathias Synthetic Communications, 2005 , vol. 35, # 3 p. 417 - 425
-
-
Route3
-
In-stock
773-64-8
-
1336-21-6
- ~%
-
In-stock
4543-58-2
References
-
THE NUTRASWEET COMPANY, (a Delaware corporation) Patent: EP299533 A2, 1989 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 60.16
- LogP 1.25926
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2,4,6-Trimethylbenzenesulfonamide sigma2,4,6-Trimethylbenzenesulfonamide manufacturer2,4,6-Trimethylbenzenesulfonamide price2,4,6-Trimethylbenzenesulfonamide structure2,4,6-Trimethylbenzenesulfonamide SDSbuy 2,4,6-Trimethylbenzenesulfonamide2,4,6-Trimethylbenzenesulfonamide supplier2,4,6-Trimethylbenzenesulfonamide uses2,4,6-Trimethylbenzenesulfonamide molecular weightprice of 2,4,6-Trimethylbenzenesulfonamide2,4,6-Trimethylbenzenesulfonamide chemical name formula of 2,4,6-Trimethylbenzenesulfonamide