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Structure of 455-68-5
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Methyl 3-fluorobenzoate is a fluorinated aromatic ester featuring a strategically positioned fluorine atom at the meta position. This electron-withdrawing substituent enhances reactivity in electrophilic substitution and improves metabolic stability in bioactive molecule design. The ester group provides a handle for downstream derivatization, enabling integration into complex synthetic pathways.
Methyl 3-fluorobenzoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to fluorinated aromatic scaffolds. Its ortho-fluoro substitution pattern facilitates directed metallation and subsequent functionalization, while the ester group offers compatibility with nucleophilic acyl substitution, reduction, and coupling reactions. Bench-stable and readily purified by distillation or chromatography, it functions effectively in multi-step syntheses of pharmaceutical intermediates and agrochemicals.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: