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Structure of 4559-70-0
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Diphenylphosphine oxide can be used as a coupling partner to prepare various organophosphorus compounds via cross-coupling reaction with aryl halides in the presence of Ni/Zn catalyst.It can also be used as a reactant to synthesize:Diphenyl(2-phenyl-2H-indazol-3-yl)phosphine oxide derivatives by phosphonylation of 2H-indazoles using rose bengal as a catalyst.Alkenyldiphenylphosphine oxides by hydrophosphinylation of terminal alkynes in the presence of transition metal catalysts.Diphenylphosphino-containing chiral ligands for asymmetric catalytic reactions via Pd-catalyzed coupling reaction with aryl triflates.Triarylphosphine oxides and Horner-Wittig reagents.
Diphenylphosphine oxide serves as a stable, bench-ready phosphine ligand precursor and versatile intermediate in transition-metal-catalyzed cross-coupling reactions. Its robustness under air and moisture facilitates handling, while its ability to participate in P–H bond formation and phosphine synthesis enables reliable access to functionalized phosphines. Functions as a key building block in the preparation of chiral ligands and catalytic systems for C–C and C–heteroatom bond constructions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: