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CS-W001157 4
Total: USD 88.00

Diphenylphosphine oxide

  • CAS No. 4559-70-0

  • Cat. No. CS-W007660
  • Purity≥95%
  • MDL No.MFCD00002079
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Diphenylphosphine oxide|CS-W007660

Structure of 4559-70-0

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Description

Diphenylphosphine oxide can be used as a coupling partner to prepare various organophosphorus compounds via cross-coupling reaction with aryl halides in the presence of Ni/Zn catalyst.It can also be used as a reactant to synthesize:Diphenyl(2-phenyl-2H-indazol-3-yl)phosphine oxide derivatives by phosphonylation of 2H-indazoles using rose bengal as a catalyst.Alkenyldiphenylphosphine oxides by hydrophosphinylation of terminal alkynes in the presence of transition metal catalysts.Diphenylphosphino-containing chiral ligands for asymmetric catalytic reactions via Pd-catalyzed coupling reaction with aryl triflates.Triarylphosphine oxides and Horner-Wittig reagents.

Application

Diphenylphosphine oxide serves as a stable, bench-ready phosphine ligand precursor and versatile intermediate in transition-metal-catalyzed cross-coupling reactions. Its robustness under air and moisture facilitates handling, while its ability to participate in P–H bond formation and phosphine synthesis enables reliable access to functionalized phosphines. Functions as a key building block in the preparation of chiral ligands and catalytic systems for C–C and C–heteroatom bond constructions.

General Information

  • CAS No. 4559-70-0
  • Cat. No. CS-W007660
  • Purity ≥95%
  • MDL No. MFCD00002079
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₁OP
  • Molecular Weight 202.19
  • Synonym(s) oxo(diphenyl)phosphonium; Diphenylphosphine oxide
  • SMILES O=P(C1=CC=CC=C1)C2=CC=CC=C2

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.1971
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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