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Structure of 459-47-2
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1-Ethyl-4-fluorobenzene is a bench-stable, electron-deficient aromatic compound featuring a para-fluoro substituent and an ethyl group. This configuration enables selective functionalization in cross-coupling reactions and provides enhanced solubility in organic solvents compared to unsubstituted analogs.
1-Ethyl-4-fluorobenzene serves as a versatile aryl fluorine building block in medicinal chemistry and materials science. Its fluorinated aromatic core exhibits enhanced metabolic stability and favorable lipophilicity, while the ethyl substituent provides a handle for further functionalization via standard coupling reactions. The molecule demonstrates excellent bench stability, ease of purification, and compatibility with common reaction conditions, enabling efficient access to complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: