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Structure of 459133-68-7
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tert-Butyl 5-bromo-3-iodo-1H-indazole-1-carboxylate features a dual halogenated indazole core with orthogonal reactivity, enabling sequential cross-coupling strategies. The tert-butyl ester provides enhanced stability and solubility in organic media, simplifying purification. This compound serves as a key scaffold for constructing complex heterocyclic architectures in medicinal chemistry and materials science.
tert-Butyl 5-bromo-3-iodo-1H-indazole-1-carboxylate serves as a versatile building block for the synthesis of functionalized indazole scaffolds. The molecule enables sequential cross-coupling reactions due to its complementary halogenation pattern, with bromo and iodo groups facilitating Pd-catalyzed couplings under standard conditions. Its tert-butyl ester group offers stability and ease of removal during late-stage functionalization. This compound is well-suited for medicinal chemistry campaigns requiring precise substitution control on the indazole core.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: