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CS-W001157 4
Total: USD 88.00

4-Chlorobutyryl chloride

  • CAS No. 4635-59-0

  • Cat. No. CS-0018490
  • Purity≥95%
  • MDL No.None
  • AREC Toxic Substance

*For research and further manufacturing use only, not for direct human use.

4-Chlorobutyryl chloride|CS-0018490

Structure of 4635-59-0

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General Information

  • CAS No. 4635-59-0
  • Cat. No. CS-0018490
  • Purity ≥95%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆Cl₂O
  • Molecular Weight 141.00
  • Synonym(s) 4-Chlorobutanoyl chloride; 4-Chlorobutanoic acid chloride; 4-Chlorobutyric acid chloride; 4-Chlorobutyroyl chloride
  • SMILES ClC(CCCCl)=O

Application

4-Chlorobutyryl chloride serves as a versatile acylating agent for the direct introduction of the 4-chlorobutyl moiety into target molecules. It enables efficient amide and ester formation under mild conditions, with good functional group tolerance and straightforward purification. The reagent exhibits high reactivity in nucleophilic acyl substitution reactions and is particularly valuable in the synthesis of bioactive intermediates and heterocyclic scaffolds where the chloroalkyl chain provides a handle for further derivatization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2927
Class : 6.1(8)
Packing Group : Ⅰ
Hazard Statements : H302-H314-H331
Precautionary Statements : P260-P264-P271-P301+P330+P331-P303+P361+P353-P305+P351+P338-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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