Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Chlorophenacylcyanide

  • CAS No. 4640-66-8

  • Cat. No. CS-M2755
  • Molecule weight179.60
  • Purity≥98%
  • MDL No.MFCD00051625

*For research and further manufacturing use only, not for direct human use.

4-Chlorophenacylcyanide|CS-M2755

Structure of 4640-66-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4640-66-8
  • Cat. No. CS-M2755
  • Purity ≥98%
  • MDL No. MFCD00051625
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆ClNO
  • Molecular Weight 179.60
  • Synonym(s) Benzenepropanenitrile, 4-chloro-beta-oxo-
  • SMILES ClC1=CC=C(C(CC#N)=O)C=C1

Description

4-Chlorophenacylcyanide features a reactive α-cyanocarbonyl moiety flanked by a para-chlorophenyl group, enabling efficient conjugation in synthetic transformations. This bench-stable reagent integrates readily into Michael addition cascades and nucleophilic substitution protocols under standard conditions.

Application

4-Chlorophenacylcyanide serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic addition and cyclization reactions. Its benzylic cyanide functionality exhibits high reactivity with amines and thiols, facilitating the synthesis of substituted pyridines, quinolines, and other nitrogen-containing heterocycles. The molecule’s bench-stable nature and compatibility with diverse functional groups make it well-suited for multi-step syntheses in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • In-stock
      Ethyl 4-chlorobenzoate|CS-W016987
      7335-27-5
    • null|null
      75-05-8
    • ~91%
    • In-stock
      4-Chlorophenacylcyanide|CS-M2755
      4640-66-8

    References

    • Kim, Bo Ram; Lee, Hyung-Geun; Kang, Seung-Beom; Jung, Kwang-Ju; Sung, Gi Hyeon; Kim, Jeum-Jong; Lee, Sang-Gyeong; Yoon, Yong-Jin Tetrahedron, 2013 , vol. 69, # 48 p. 10331 - 10336
  • Route2
    • null|null
      122-01-0
    • null|null
      372-09-8
    • ~78%
    • In-stock
      4-Chlorophenacylcyanide|CS-M2755
      4640-66-8

    References

    • Nowill, Randall W.; Patel, Trisha J.; Beasley, David L.; Alvarez, Jose A.; Jackson III, Elizah; Hizer, Todd J.; Ghiviriga, Ion; Mateer, Scott C.; Feske, Brent D. Tetrahedron Letters, 2011 , vol. 52, # 19 p. 2440 - 2442
  • Route3
    • In-stock
      Methyl 4-chlorobenzoate|CS-B1786
      1126-46-1
    • null|null
      75-05-8
    • ~76%
    • In-stock
      4-Chlorophenacylcyanide|CS-M2755
      4640-66-8

    References

    • Takahashi, Toshiyuki; Sakuraba, Aya; Hirohashi, Tomoko; Shibata, Takunobu; Hirose, Masaaki; Haga, Yuji; Nonoshita, Katsumasa; Kanno, Tetsuya; Ito, Junko; Iwaasa, Hisashi; Kanatani, Akio; Fukami, Takehiro; Sato, Nagaaki Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7501 - 7511

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.86
  • LogP   2.43638
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Chlorophenacylcyanide sigma4-Chlorophenacylcyanide manufacturer4-Chlorophenacylcyanide price4-Chlorophenacylcyanide structure4-Chlorophenacylcyanide SDSbuy 4-Chlorophenacylcyanide4-Chlorophenacylcyanide supplier4-Chlorophenacylcyanide uses4-Chlorophenacylcyanide molecular weightprice of 4-Chlorophenacylcyanide4-Chlorophenacylcyanide chemical name formula of 4-Chlorophenacylcyanide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label